6533b82afe1ef96bd128b674

RESEARCH PRODUCT

A novel synthesis of chain-extended amino sugar derivatives through aza-Cope rearrangement of N-galactosyl-N-homoallylamines

Horst KunzSandrine Deloisy

subject

chemistry.chemical_classificationAmino sugarchemistryChain (algebraic topology)StereochemistryYield (chemistry)Organic ChemistryDrug DiscoveryAza-Cope rearrangementOrganic chemistryStereoselectivityBiochemistry

description

Abstract Chain-extended amino sugars are synthesized via stereocontrolled Lewis acid-catalyzed aza-Cope rearrangement of N-glycosyl homoallylamines in high yield and stereoselectivity.

https://doi.org/10.1016/s0040-4039(97)10720-1