6533b82afe1ef96bd128b676

RESEARCH PRODUCT

How to Bridge the Gap Between Membrane Biology and Polymer Science

Helmut RingsdorfBrigitta Schmidt

subject

chemistry.chemical_classificationLiposomeMaterials scienceCellMembrane biologyPolymerMembrane compositionCell membranemedicine.anatomical_structureMembranechemistryMonolayermedicineBiophysics

description

Can polymer chemists contribute to the understanding or even mimicking of cell membrane functions and cell-cell interactions? Fascinated by the specificity and efficiency of, for example, the destruction of tumor cells by lymphocytes (1) and having in mind what biochemical analyses tell us about membrane composition, we may try to “synthesize” membrane and cell models. The commonly used model systems, such as planar lipid monolayers at the gas-water interface, bimolecular lipid membranes and spherical liposomes, are much less stable than natural membrane systems (Figure 1).

https://doi.org/10.1007/978-94-009-4712-2_25