6533b82afe1ef96bd128b82c

RESEARCH PRODUCT

Genetic heterogeneity and recombination in human type 2 astroviruses

Krisztián BányaiFabio TummoloAdriana CalderaroP. PintoS. De GraziaFloriana BonuraMaria Cristina MediciP. MoschidouVito MartellaGiovanni M. Giammanco

subject

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia Clinicafood.ingredientMolecular Sequence DataBiologyGenomelaw.inventionGenetic HeterogeneityOpen Reading FramesfoodPhylogeneticslawVirologyCluster AnalysisHumansPhylogenyRecombination GeneticGeneticsGenetic heterogeneityStrain (biology)MamastrovirusSequence Analysis DNAOpen reading frameRecombinant DNARNA Viralastrovirus genotyping ItalyRecombinationMamastrovirus

description

ABSTRACT Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3′ end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.

10.1128/jcm.02102-12.http://hdl.handle.net/10447/77925