6533b82afe1ef96bd128b8bc

RESEARCH PRODUCT

The collagen receptor subfamily of the integrins

Santeri PuranenJyrki HeinoMark S. JohnsonDaniel J. White

subject

IntegrinsReceptors CollagenSubfamilybiologyChemistryIntegrinCell BiologyPlasma protein bindingLigandsBiochemistryProtein Structure TertiaryCollagen receptorCell biologyIntegrin alpha Mbiology.proteinAnimalsHumansSignal transductionReceptorFunction (biology)Protein BindingSignal Transduction

description

The four collagen receptor integrins, alpha1beta1, alpha2beta1, alpha10beta1 and alpha11beta1, form a structurally and functionally distinct subgroup when compared to other members of the integrin family. In this review, we discuss the structures of these receptors and their differences in collagen binding and signalling function.

https://doi.org/10.1016/j.biocel.2003.08.016