6533b82afe1ef96bd128ba7b
RESEARCH PRODUCT
Crystal structure of 5-(5,6-dihydrobenzo[4,5]imidazo[1,2-c]quinazolin-6-yl)-2-methoxyphenol
Arafath MaMohd. R. RazaliRosenani AhFarook Adamsubject
Benzimidazolecrystal structurecyclizationCrystallographyHydrogen bondGeneral ChemistryCrystal structureDihedral angleCondensed Matter PhysicsRing (chemistry)BioinformaticsMedicinal chemistryData Reportschemistry.chemical_compoundchemistryQD901-999QuinazolineMoietyGeneral Materials Scienceimidazole derivativeBenzenedescription
In the molecule of the title compound, C21H17N3O2, the 5,6-dihydrobenzimidazo[1,2-c]quinazoline moiety is disordered over two orientations about a pseudo-mirror plane, with a refined occupancy ratio of 0.863 (2):0.137 (2). The dihedral angles formed by the benzimidazole ring system and the benzene ring of the quinazoline group are 14.28 (5) and 4.7 (3)° for the major and minor disorder components, respectively. An intramolecular O—H...O hydrogen bond is present. In the crystal, molecules are linked by O—H...N hydrogen bonds, forming chains running parallel to [10-1].
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-11-21 | Acta Crystallographica Section E: Crystallographic Communications |