6533b82afe1ef96bd128c274
RESEARCH PRODUCT
Lateral differences in GABA binding sites in rat brain.
Federico PiccoliP. GuarneriF. ScoppaR. GuarneriS ScondottoV. La Bellasubject
MaleCerebellumThalamusCentral nervous systemHippocampusStriatumBiochemistryHippocampusFunctional LateralityCellular and Molecular NeurosciencemedicineAnimalsBinding siteCerebral CortexBinding SitesChemistryBrainRats Inbred StrainsGeneral MedicineReceptors GABA-AhumanitiesCorpus StriatumRatsmedicine.anatomical_structurenervous systemCerebral cortexCerebral hemisphereNeurosciencedescription
An asymmetric distribution of GABA binding sites was found in the cerebral cortex, hippocampus, cerebellar hemispheres, striatum, and thalamus. Higher levels of [3H]GABA binding were observed in the left-side of most brain areas and in a greater percentage of adult rats, but the opposite asymmetry was found in the thalamus. A similar left-right difference in cerebral hemispheres was also found in five day-old rats, suggesting the genetic predetermination of asymmetry.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1988-03-01 | Neurochemical research |