6533b82afe1ef96bd128c2a1

RESEARCH PRODUCT

Accuracy of Nasal Pressure Swing to Predict Failure of High-Flow Nasal Oxygen in Patients with Acute Hypoxemic Respiratory Failure

Roberto TonelliAndrea CortegianiRiccardo FantiniLuca TabbìIvana CastaniereGiulia BruzziStefano BusaniLorenzo BallClini Enrico MAlessandro Marchioni

subject

Pulmonary and Respiratory Medicineself-inflicted lung injuryacute respiratory failurenon-invasive mechanical ventilationhigh flow nasal cannulaesophageal pressure swingshigh flow nasal cannulaacute respiratory failure high flow nasal cannula non-invasive mechanical ventilation esophageal pressure swings nasal pressure swings respiratory monitoring inspiratory effort self-inflicted lung injurynasal pressure swingsCritical Care and Intensive Care MedicineAcute respiratory failurerespiratory monitoringinspiratory effort

description

In a real-life cohort of patients with AHRF undergoing HFNO, ΔPnose showed excellent accuracy in predicting early failure, similar of that displayed by ROX. Giving that the decision to upgrade to NIV or MV was based on clinical variables, the high accuracy of ROX in predicting failure of HFNO is not surprising. The similar accuracy of ΔPnose (the only measurement that remained blinded to our clinical decision), strengthened the association with outcome, avoiding incorporation bias.

yearjournalcountryeditionlanguage
2023-03-15
10.1164/rccm.202210-1848lehttps://pure.amc.nl/en/publications/accuracy-of-nasal-pressure-swing-to-predict-failure-of-highflow-nasal-oxygen-in-patients-with-acute-hypoxemic-respiratory-failure(14c5a916-ee74-43e7-a71d-ae4ee406472c).html