6533b82afe1ef96bd128c470

RESEARCH PRODUCT

The Palliative Care in the Metastatic Spinal Tumors. A Systematic Review on the Radiotherapy and Surgical Perspective

Giuseppe GiammalvaGianluca FeriniFabio TorregrossaLara BrunassoSofia MussoUmberto BenignoRosa GerardiLapo BonosiRoberta CostanzoFederica PaoliniPaolo PalmiscianoGiuseppe UmanaRina Di BonaventuraCarmelo L. SturialeDomenico IacopinoRosario Maugeri

subject

palliative carequality of lifespinal metastasisSpace and Planetary Sciencespinal cord stimulationSettore MED/27 - NeurochirurgiaPaleontologyradiofrequency ablationGeneral Biochemistry Genetics and Molecular BiologyEcology Evolution Behavior and Systematicsradiotherapyvertebral augmentation

description

Spine represents the most common site for metastatic disease involvement. Due to the close relationship between the spinal cord and critical structures, therapeutic management of spinal metastases remains challenging. Spinal localization can lead to neurological sequelae, which can significantly affect the quality of life in patients with a limited life expectancy. The authors conducted a systematic literature review according to PRISMA guidelines in order to determine the impact of the most updated palliative care on spinal metastases. The initial literature search retrieved 2526 articles, manually screened based on detailed exclusion criteria. Finally, 65 studies met the inclusion criteria and were finally included in the systematic review. In the wide scenario of palliative care, nowadays, recent medical or surgical treatments represent valuable options for ameliorating pain and improving patients QoL in such this condition.

10.3390/life12040571http://hdl.handle.net/10447/556830