6533b82afe1ef96bd128c7b8
RESEARCH PRODUCT
SELECTIVE G-QUADRUPLEX STABILIZERS: SALPHEN-LIKE COMPLEXES WITH ANTIPROLIFERATIVE ACTIVITY
Alessio TerenziRiccardo BonsignoreCarla GentileAnnamaria MartoranaGiampaolo BaroneAntonino LauriaAnna Maria Almericosubject
G-QUADRUPLEX STABILIZERS Schiff base complexes hTelo and c-myc G-quadruplexes DNASettore CHIM/03 - Chimica Generale E InorganicaSettore BIO/10 - BiochimicaSettore CHIM/08 - Chimica Farmaceuticadescription
Schiff base complexes derived from N,N!-bridged tetradentate ligands involving N2O2 donor atoms present very favourable features to act as G4 binders. Thus, a series of square-planar and square pyramidal metal complexes, ML2+ (M = Ni, Cu, and Zn), have been synthesized and characterized.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-01-01 |