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RESEARCH PRODUCT
Anticancer Activity of Salvia miltiorrhiza and Its Secondary Metabolites
Thomas EfferthChing-fen Wusubject
chemistry.chemical_compoundTraditional medicinechemistryMedicinal herbsPhenolic acidSalvia miltiorrhizadescription
Salvia miltiorrhiza Bunge (danshen) is a well-known traditional Chinese medicinal herb. The root part of the plant contains most of the bioactive ingredients, which mainly belong to two groups of compounds: hydrophilic phenolic acids and hydrophobic tanshinones. These bioactive compounds refer to as secondary metabolites and exert multiple therapeutic activities, such as anti-oxidative stress, anti-neurodegenerative, anti-inflammatory, and anti-hypertensive effects without showing serious side effects. Besides these pharmacological activities, anticancer effects have also attracted scientific attention. This review will provide an updated summary of the anticancer effects and the proposed mechanisms of the major bioactive compounds isolated from S. miltiorrhiza.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-01-01 |