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RESEARCH PRODUCT

Bioreactivity of Resveratrol Toward Inflammation Processes

subject

description

Grape polyphenols are abundant. They play essential roles in the vine’s life, particularly in its defense mechanisms. Interestingly, the grape, fresh or dried, is a widely consumed fruit by humans, as are its processed products, grape juice and wine. Moreover, they contain vast and highly varied quantities of polyphenols. Like other phytophenols, grape and wine resveratrol is considered a protective micronutrient like flavonoids, epicatechins in green tea and cocoa, quercetin in apples and onions, curcumin of the turmeric root, and hydroxytyrosol in olive oil. Resveratrol is a powerful natural antioxidant in vine. Interestingly, in humans, it protects low density lipoproteins against oxidation and consequently prevents or delays atherosclerosis. On the other hand, inflammation is the reflect of many dysfunctions or pathologies, where resveratrol has a positive effect against these disorders. This review will summarize resveratrol anti-inflammatory properties and mechanisms toward arthritis and retinopathies.