6533b82bfe1ef96bd128cda9
RESEARCH PRODUCT
Regulatory mechanisms of estrogen on vascular ageing
Carlos EhermenegildoYlva HellstenSusana NovellaAna Paula Dantassubject
AgingEndotheliumArticle Subjectbusiness.industrymedicine.drug_classlcsh:CytologyEstrogensCell BiologyGeneral MedicineBioinformaticsBiochemistryVascular ageingmedicine.anatomical_structureText miningEditorialEstrogenMedicineHumansFisiologia humanaFemaleEndothelium Vascularlcsh:QH573-671businessSistema cardiovasculardescription
Women can be considered hemodynamically younger than men of the same age, based on epidemiological studies establishing that the incidence of vascular diseases in women is relatively lower compared to that in aged-matched men. However, after menopause, these numbers increase to values that are close to those found in men. Vascular ageing is associated with structural and functional changes of the vascular wall, including endothelial dysfunction, arterial stiffening, and remodelling, as well as impaired angiogenesis, which become major risk factors in the development of cardiovascular disease.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 |