6533b82bfe1ef96bd128d55f
RESEARCH PRODUCT
false
subject
CouplingMultidisciplinaryAggregate (data warehouse)Blood flow01 natural sciencesMesh free010305 fluids & plasmas010101 applied mathematicsFlow (mathematics)Blood vessel prosthesis0103 physical sciencesFluid dynamics0101 mathematicsMembrane surfaceBiological systemdescription
We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling the hydrodynamics in flexible biological valves. In the first part of this study, the method is successfully validated against both traditional modelling techniques and experimental data. In the second part, it is further developed to account for the formation of solid aggregates in the flow and at the membrane surface. Simulations of various types of aggregates highlight the main benefits of discrete multi-physics and indicate the potential of this approach for coupling the hydrodynamics with phenomena such as clotting and calcification in biological valves.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-04-06 | PLOS ONE |