6533b82bfe1ef96bd128df18

RESEARCH PRODUCT

Protein-Membrane Interaction

Jan Becker

subject

Streptavidinchemistry.chemical_compoundMembraneMaterials sciencechemistryBiotinBiophysicsParticleNanorodLipid bilayerSpectroscopyPlasmon

description

In the following chapter I present a nanosized and addressable protein sensor platform based on membrane coated plasmonic particles. I show unequivocally the covering of gold nanorods with lipid bilayers and thereafter the subsequent detection of streptavidin binding to biotin moities in the lipids. The binding of the streptavidin on the membrane covered gold nanorods is detected by monitoring the spectral shift by fast single particle spectroscopy (fastSPS) on many particles in parallel.

https://doi.org/10.1007/978-3-642-31241-0_7