6533b82bfe1ef96bd128e0b5
RESEARCH PRODUCT
Genetic control of C3 production by the S region of the mouse MHC.
Guido SireciAlfredo SalernoDomenico LioFrancesco Dielisubject
MaleGeneticsRatónImmunologyHaplotypeH-2 AntigensCongenicMice Inbred StrainsComplement C3ImmunogeneticsBiologyMajor histocompatibility complexHemolysisMajor Histocompatibility ComplexMiceGene Expression RegulationHaplotypesGeneticsbiology.proteinAnimalsAllelesdescription
SUMMARY The present paper reports evidence indicating that the level of the third complement component (C3) is regulated by the S region of the murine H-2 complex. In fact, using congenic strains of mice we demonstrate that mice with the k haplotype at the S region show high C3 levels, whereas mice with the d haplotype at the S region show low C3 levels.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1988-10-01 |