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RESEARCH PRODUCT
Electro-organic Synthesis as a Sustainable Alternative for Dehydrogenative Cross-Coupling of Phenols and Naphthols
Robert FrankeKatrin Marie DyballaSiegfried R. WaldvogelBarbara Riehlsubject
Chemical substance010405 organic chemistryChemistryAnodic oxidationOrganic Chemistry010402 general chemistry01 natural sciencesCatalysis0104 chemical scienceschemistry.chemical_compoundCoupling (computer programming)Organic chemistryOrganic synthesisPhenolsdescription
The dehydrogenative cross-coupling of phenols and naphthols can be achieved by several oxidative methods. However, the key is the use of fluorinated alcohols such as 1,1,1,3,3,3-hexafluoroisopropanol. The direct application of electricity represents an alternative synthetic approach, which is superior to other oxidizers (e.g., peroxides). The method is sustainable, inherently safe, and easily scalable.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-10-18 | Synthesis |