6533b82cfe1ef96bd128e919

RESEARCH PRODUCT

ChemInform Abstract: Synthesis of (-)-Auricularic Acid and its C-4 Epimer. The Absolute Configuration of Auricularic Acid.

Manuel ArnóRamón J. ZaragozáMiguel PeiróAntonio Abad

subject

TerpeneStereochemistryChemistryAbsolute configurationEpimerGeneral Medicine

description

Abstract A synthesis of (−)-auricularic acid (2a) starting from methyl (+)-13-oxo- podocarp-8(14)-en-19-oate (3a) and a synthesis of its C-4 epimer (2b) starting from methyl (+)-13-oxopodocarp-8(14)-en-18-oate (3b) are described. The absolute configuration of natural auricularic acid is stablished as (4R, 5S, 8S, 9R, 10S, 14S).

yearjournalcountryeditionlanguage
2010-08-22ChemInform
https://doi.org/10.1002/chin.199132224