6533b82cfe1ef96bd128e96a
RESEARCH PRODUCT
Zur Wirkung von Muskelrelaxantien auf den intraokularen Druck
Jantzen JpKleemann Ppsubject
Intraocular pressuregenetic structuresbusiness.industryDepolarizing muscle relaxantsFast onsetSystemic circulationeye diseasesOphthalmologyAnesthesiaAnestheticMedicinesense organsbusinessOphthalmic surgerymedicine.drugdescription
Since general anesthesia is being used increasingly in ophthalmic surgery, the effects of anesthetic drugs on intraocular pressure (IOP) have to be considered. Competitive neuromuscular blocking drugs either do not affect IOP or produce a slight decrease. Depolarizing muscle relaxants increase IOP. This effect, which is pronounced with succinylcholine, cannot be reliably prevented by any concomitant medication. The new competitive relaxants atracurium and vecuronium provide stable conditions with respect to IOP and systemic circulation, combined with fast onset and intermediate duration of action.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1988-07-01 | Klinische Monatsblätter für Augenheilkunde |