ChemInform Abstract: Synthesis and anti-Staphylococcal Activity of New Halogenated Pyrroles Related to Pyrrolomycins F.

6533b82cfe1ef96bd128e9e2

RESEARCH PRODUCT

ChemInform Abstract: Synthesis and anti-Staphylococcal Activity of New Halogenated Pyrroles Related to Pyrrolomycins F.

Salvatore Petruso Domenico Schillaci Maria Valeria Raimondi

subject

inorganic chemicals Strain (chemistry)Stereochemistry Chemistry Structure–activity relationship General Medicine Antibacterial activity Chemical synthesis Pyrrole derivatives

description

The chemical synthesis of new halogenated pyrroles related to pyrrolomycins F is described and the anti-staphylococcal activity compared. The replacement of 4′-bromo atom of parent compounds with two chloro atoms at 3′ and 5′ position increase the antibacterial activity against a reference strain of S. aureus.

year	journal	country	edition	language
2008-03-18	ChemInform

https://doi.org/10.1002/chin.200812109

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