6533b82cfe1ef96bd128eff9

RESEARCH PRODUCT

C. HYSTOLITICUM RECOMBINANT COLLAGENASES AND METHOD FOR THE MANUFACTURE THEREOF

F BertuzziA CuttittaS MazzolaM SalamoneGiulio GhersiGregorio Seidita

subject

Settore BIO/13 - Biologia ApplicataCOLLAGENASESSettore BIO/10 - BiochimicaCELL TERAPYDIABET 1RECOMBINANT PROTEIN

description

The present invention relates to the production of recombinant collagenases, and in particular describes a method for the production of recombinant clostridium histolyticum collagenases Col characterized by a yield higher than approximately 140 mg/l of culture of said collagenases in soluble, biologically active form, collagenases produced by this method, compositions comprising these collagenases and the use thereof.

http://hdl.handle.net/10447/59868