6533b82cfe1ef96bd128f155

RESEARCH PRODUCT

Unshared binding sites for Bacillus thuringiensis Cry3Aa and Cry3Ca proteins in the weevil Cylas puncticollis (Brentidae)

Patricia Hernández-martínezNatalia Mara Vera-velascoBaltasar Escriche

subject

endocrine systemAfrican sweetpotato weevilBacillus thuringiensis ToxinsShort CommunicationBinding sitesInsect controlfungiBacillus thuringiensisToxicologyBinding CompetitiveInsect resistance managementEndotoxinsHemolysin ProteinsInsecticidal proteinsBacterial ProteinsAnimalsWeevils

description

Bacillus thuringiensis Cry3Aa and Cry3Ca proteins have been reported to be toxic against the African sweetpotato pest Cylas puncticollis. In the present work, the binding sites of these proteins in C. puncticollis brush border vesicles suggest the occurrence of different binding sites, but only one of them is shared. Our results suggest that pest resistance mediated by alteration of the shared Cry-receptor binding site might not render both Cry proteins ineffective.

yearjournalcountryeditionlanguage
2016-11-01Toxicon
10.1016/j.toxicon.2016.09.014http://europepmc.org/articles/PMC5090047