6533b82cfe1ef96bd128fef7
RESEARCH PRODUCT
Polypeptides controlling hematopoietic cell development and activation. I. In vitro results.
Friedhelm HerrmannRoland Mertelsmannsubject
medicine.medical_specialtymedicine.medical_treatmentBiologylaw.inventionBlood celllawInternal medicinemedicineAnimalsHumansProgenitor cellGrowth SubstancesCells CulturedHematologyCell growthGrowth factorHematologyGeneral MedicineHematopoietic Stem CellsIn vitroCell biologyHematopoiesisHaematopoiesismedicine.anatomical_structureImmunologyRecombinant DNAPeptidesdescription
Recombinant DNA technology has been central in answering some of the most relevant questions in the research of regulation of the functional status of hematopoietic progenitor cells and their progeny. This leading article will focus on recent results that have emerged from studies utilizing recombinant molecules that control hematopoietic blood cell development and activation. The following features will be detailed: The molecular and biological characteristics and biochemistry of hematopoietic growth factors, synergizing factors and releasing factors, their role in the regulation of hematopoiesis and activation of normal and leukemic cells, their cellular sources, and regulation of production.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-03-01 | Blut |