6533b82cfe1ef96bd12900d8
RESEARCH PRODUCT
N‐[tert‐Butoxycarbonylglycyl‐(Z)‐α,β‐dehydrophenylalanylglycyl‐(E)‐α,β‐dehydrophenylalanyl]glycine methyl ester dihydrate
Marek LisowskiAnna MaciągTadeusz LisMaciej Makowskisubject
ChemistryHydrogen bondStereochemistryIntramolecular forceIntermolecular forceGlycine methyl esterGeneral Materials ScienceTert-butoxySequence (biology)General ChemistryCrystal structureCondensed Matter PhysicsPentapeptide repeatdescription
The title pentapeptide, Boc0—Gly1–ΔZPhe2—Gly3–ΔEPhe4—Gly5—OMe, C30H35N5O8·2H2O, adopts the type I β-turn conformation for the ΔZPhe2—Gly3 residues. It is stabilized by a 4\rightarrow1 intramolecular hydrogen bond between the ΔEPhe4 NH and Gly1 CO groups. All the amino acid residues in the pentapeptide sequence are linked trans to each other. The crystal structure is stabilized by intra- and intermolecular hydrogen bonds.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2006-01-27 | Acta Crystallographica Section E-Structure Reports Online |