6533b82dfe1ef96bd1290b84
RESEARCH PRODUCT
Synthesis of pyrazolo[4,3-c][1,2,6]benzothiadiazocine, a new ring system as potential COX inhibitor
Onofrio MigliaraVirginia SpanòPatrizia DianaBarbara ParrinoCristina CianciminoSpanòsubject
lcsh:QD241-441chemistry.chemical_compoundCOX Inhibitorlcsh:Organic chemistryChemistryStereochemistry[126]Benzothiadiazocine 14-dihydropyrazolo[43-c][126benzothiadiazocin-11(10H)one 55-dioxides pyrazole COX inhibitorsOrganic ChemistryPyrazoleRing (chemistry)Settore CHIM/08 - Chimica Farmaceuticadescription
Derivatives of the new ring system 1,4-dihydropyrazolo[4,3-c][1,2,6] benzothiadiazocin-11(10H)one 5,5-dioxide were synthesized in five or six steps in 57-66% overall yields and tested as COX inhibitors.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-03-19 | ARKIVOC |