Synthesis of ?-fucosyl glycosides and disaccharides using 4-methoxybenzyl (Mpm) protected fucosyl donors

6533b82dfe1ef96bd12912df

RESEARCH PRODUCT

Synthesis of ?-fucosyl glycosides and disaccharides using 4-methoxybenzyl (Mpm) protected fucosyl donors

subject

chemistry.chemical_classification chemistry.chemical_compound Double bond chemistry Stereochemistry medicine Glycoside Stereoselectivity Chloride Fucose medicine.drug

description

The 4-methoxybenzyl (Mpm) group removable by selective oxidation was applied as a nonneighbouring-group-active protection of fucose hydroxy functions in the stereoselective synthesis of α-fucosides of acceptors containing double bonds sensitive to hydrogenation. With this aim, the synthesis of the α-fucosyl chloride (4) carrying the acidsensitive Mpm protection was elaborated.

year	journal	country	edition	language
1992-01-01	Journal f�r Praktische Chemie/Chemiker-Zeitung

https://doi.org/10.1002/prac.19923340706

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