6533b82dfe1ef96bd12913e3
RESEARCH PRODUCT
Anodic Dehydrogenative Cyanamidation of Thioethers: Simple and Sustainable Synthesis of N‐Cyanosulfilimines
Martin KleinSiegfried R. Waldvogelsubject
chemistry.chemical_classificationGreen chemistry540 Chemistry and allied sciencesSulfideElectroorganic Synthesisgreen chemistryCommunicationchemistry.chemical_elementPeriodateGeneral Chemistryoxidative imidationElectrochemistryCombinatorial chemistryCatalysisCommunicationsAnodechemistry.chemical_compoundchemistryelectrochemistrySimple (abstract algebra)540 Chemiedehydrogenative couplingCarbonsulfiliminesdescription
Abstract A novel and very simple to perform electrochemical approach for the synthesis of several N‐cyanosulfilimines in good to excellent yields was established. This method provides access to biologically relevant sulfoximines by consecutive oxidation using electro‐generated periodate. This route can be easily scaled‐up to gram quantities. The S,N coupling is carried out at an inexpensive carbon anode by direct oxidation of sulfide. Therefore, the designed process is atom economic and represents a new “green route” for the synthesis of sulfilimines and sulfoximines.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-09-22 | Angewandte Chemie (International Ed. in English) |