6533b82dfe1ef96bd12915aa

RESEARCH PRODUCT

Late onset of unilateral optic disk edema secondary to treatment with imatinib mesylate

Melania CarlisiVincenzo AccursoSalvatrice MancusoMarco SantoroMariasanta NapolitanoGiuseppe TarantinoSergio SiragusaSimona Raso

subject

Adverse event0301 basic medicinegenetic structuresmedicine.drug_classOptic Disk EdemaLate onsetCase ReportClinical manifestationCase ReportsTyrosine-kinase inhibitor03 medical and health sciences0302 clinical medicinechronic myeloid leukemiatyrosine kinase inhibitorsmedicineIn patientAdverse effectbusiness.industryoptic disk edemaImatinibGeneral Medicineeye diseases030104 developmental biologyImatinib mesylateimatiniboptic nerve edemaAnesthesiaAdverse events030221 ophthalmology & optometrybusinessmedicine.drug

description

Key Clinical Message Prompt ophthalmology evaluation and immediate imatinib suspension should be suggested at any time of tyrosine kinase inhibitor therapy in patients with visual deficit, as it may be a clinical manifestation of optic disk edema, and suspension may help in prompt recovery.

10.1002/ccr3.1137http://europepmc.org/articles/PMC5628210