6533b82dfe1ef96bd1291c08

RESEARCH PRODUCT

Chaperones: General Characteristics and Classifications

Alberto J.l. MacarioFrancesco CappelloEverly Conway De Macario

subject

Chaperone (protein)biology.proteinHuman genomeComputational biologyBiologyOrganism

description

This chapter presents the classification of chaperones, their molecular properties among which that of forming functional complexes involving various molecules, and their distribution inside and outside the cell. The chaperone genes in the human genome are listed and briefly described, focusing on the small heat-shock proteins (sHsp), Hsp60, Hsp70, and Hsp90, and mentioning all others known. The chapter also introduces the concept of chaperoning system, i.e., the physiological system of an organism which is composed of all its chaperones, co-chaperones, and chaperone co-factors.

yearjournalcountryeditionlanguage
2013-01-01
https://doi.org/10.1007/978-94-007-4667-1_2