6533b82dfe1ef96bd1291dcc

RESEARCH PRODUCT

Brain and Breathing

Maria R. BonsignoreOreste Marrone

subject

Control of breathingmedicine.medical_specialtySleep Stagesbusiness.industrySettore MED/10 - Malattie Dell'Apparato RespiratorioSleep in non-human animalsSleep deprivationControl of respirationSleep and breathingInternal medicinephysiologyBreathingCardiologyMedicineWakefulnessmedicine.symptomRespiratory systembusiness

description

Breathing is an essential feature of living organisms, and control of breathing is a very complex topic in human physiology. Breathing is differently modulated under conditions of wakefulness and sleep, and ventilation decreases during sleep in normal subjects. In patients with respiratory diseases, sleep represents a very vulnerable condition, since gas exchange usually worsens, especially in REM sleep. Several types of respiratory events can occur during sleep, and knowledge of control of breathing is essential to understand their pathophysiology. This chapter summarizes the main characteristics of ventilation during both wakefulness and sleep, the differences found between genders, and the effects of sleep deprivation/fragmentation on control of breathing, with special attention to metabolic control of ventilation which plays a major role in maintaining arterial blood gases homeostasis.

yearjournalcountryeditionlanguage
2014-01-01
https://doi.org/10.1007/978-88-470-5388-5_19