6533b82efe1ef96bd1292763
RESEARCH PRODUCT
Delayed postnatal neurogenesis in the cerebral cortex of lizards
Isidro FerrerJosé Manuel García-verdugoA. MolownyCarlos Lopez-garciasubject
Cerebral CortexEpendymal CellMedial cortexHippocampusLizardsAnatomyGranular layerBiologyInner plexiform layerbiology.organism_classificationPodarcis hispanicaMicroscopy Electronmedicine.anatomical_structureDevelopmental NeuroscienceCerebral cortexmedicineAnimalsAutoradiographyFascia dentataCell DivisionThymidineDevelopmental Biologydescription
Labelled cells were consistently observed in the medial cortex of the lizard brain after i.p. injections of tritiated thymidine (5 microCi/g b. wt.), 1, 7, 18 or 28 days of survival and posterior autoradiographic evaluation. In 3 groups of specimens (postnatal, young and adult) of the species Podarcis hispanica, after one day of survival, labelled cells were located in the ependymal cell layer underlying the medial cortex. After intermediate survival times (7, 18 days), labelled cells were found in 3 zones: the ependymal layer, the inner plexiform layer and the granular layer. After one month of survival, most labelled cells were observed in the granular layer. In the granular layer, these cells were distributed at random. These results show that postnatal neurogenesis in the medial cortex of the lizard occurs following a spatio-temporal pattern reminiscent of that found in the fascia dentata of the mammalian hippocampus.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1988-10-01 | Developmental Brain Research |