TISSUE ENGINEERING FOR THE DEVELOPMENT OF THREE-DIMENSIONAL INVITRO MODELS OF HUMAN MUCOSAE

6533b82efe1ef96bd1292dfd

RESEARCH PRODUCT

TISSUE ENGINEERING FOR THE DEVELOPMENT OF THREE-DIMENSIONAL INVITRO MODELS OF HUMAN MUCOSAE

Alberto Giuseppe Fucarino Salvatore Montesanto Alessandro Pitruzzella Antonella Marino Gammazza Felicia Farina Valerio Maria Bartolo Brucato Vincenzo La Carrubba Giovanni Zummo Fabio Bucchieri R Abbate R Marchese

subject

Settore BIO/16 - Anatomia Umana tissue engineering human mucosae 3d models cunt scaffolds

description

Traditional two-dimensional (2D) cell cultures only partially reflect the morpho-molecular pattern of human cells in tissues, and they are also unable to fully mimic the complexity of the in vivo microenvironment. Cell development in in vivo systems differs significantly from classical 2D cell culture models, especially with regard to the morphology, growth kinetics, gene expression and the degree of differentiation. Tissue engineering allows the reproduction of tissues by cell seeding on biocompatible scaffolds, to form a homogenous ...

year	journal	country	edition	language
2014-01-01

http://hdl.handle.net/10447/104373

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