6533b82efe1ef96bd129313d

RESEARCH PRODUCT

Sequiterpene-related compounds as endocrine disrupters in Oncopeltus fasciatus, and potential reduced glutathione synthesis modifiers

M. Dolores GarceráAmelia CerveraR. MartínezAna C Maymó

subject

chemistry.chemical_classificationEnvironmental EngineeringChemical compoundStereochemistryChemical structureBiological activityGlutathioneBiologySesquiterpenePollutionchemistry.chemical_compoundMechanism of actionchemistryBiochemistryEndocrine disruptormedicineEnvironmental Chemistrymedicine.symptomWaste Management and DisposalLactone

description

Sesquiterpene lactones have been found to exhibit effects on insect growth and development. In this study, the bioactivity of natural lactones extracted from Centaurea mariolensis and some structurally related synthetic derivatives has been investigated. Assays have also been carried out in order to determine the potential of these lactones as modifiers of reduced glutathione (GSH) synthesis.

https://doi.org/10.1016/s0048-9697(99)00222-3