6533b82efe1ef96bd1294472

RESEARCH PRODUCT

ChemInform Abstract: Synthesis of Isoxazoline Derivatives Through Boulton-Katritzky Rearrangement of 1,2,4-Oxadiazoles.

Antonio Palumbo PiccionelloSilvestre BuscemiAndrea PaceAnnalisa Guarcello

subject

ChemistrySide chainGeneral MedicineMedicinal chemistry

description

This is the first report of the rearrangement of 1,2,4-oxadiazole with saturated C—C—O side chains and an unusual example of an irreversible rearrangement that allows the formation of nonaromatic heterocycles.

https://doi.org/10.1002/chin.201334125