6533b82efe1ef96bd1294587
RESEARCH PRODUCT
On-line high-pressure extraction-high-performance liquid chromatography
P. RoumeliotisK.k. Ungersubject
CouplingChromatographyChemistryOrganic ChemistryExtraction (chemistry)Analytical chemistryGeneral MedicineInjectorBiochemistryHigh-performance liquid chromatographyLine (electrical engineering)Analytical Chemistrylaw.inventionLoop (topology)Sampling (signal processing)lawBar (unit)description
Abstract A coupling unit is described that allows on-line operation of a high-pressure extraction apparatus with a high-performance liquid chromatograph. The unit consists of two high-pressure sample-injection valves, connected in series. The first valve operates as a switching valve to the loop and controls the release of pressure along a packed microbore column. Two short, packed microbore columns are positioned between the first and second valve, sampling the extracted compounds over a desired period and simultaneously operating as sample loop for the second valve; the latter is the injector for the high-performance liquid chromatographic column. The unit was tested by continuous extraction of valtrate and didrovaltrate from Radix valerianae with carbon dioxide at 313°K and 96 bar.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1983-12-01 | Journal of Chromatography A |