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RESEARCH PRODUCT
Radioactively labelled epoxides. Part IV. Tritium labelled α- and β-methyl styrene oxides
Karl L. PlattAlan J. SparrowFranz Oeschsubject
Tritiated waterOrganic ChemistrySequence (biology)BiochemistryAnalytical ChemistryStyrenechemistry.chemical_compoundchemistryStyrene oxideDrug DiscoveryOrganic chemistryRadiology Nuclear Medicine and imagingTritiumSpectroscopyCis–trans isomerismdescription
Tritium labelled α-methyl styrene oxide (2-methyl-2-phenyloxirane) and cis- and trans-β-methyl styrene oxides (Z- and E-2-methyl-3-phenyl oxirane) have been prepared using tritiated water as the inexpensive source of tritium. The two geometrical isomers of β-methyl styrene oxide were synthesized by a sequence of reactions which led to stereochemically pure products, and obviated any need to separate the isomers.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1983-11-01 | Journal of Labelled Compounds and Radiopharmaceuticals |