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RESEARCH PRODUCT

Problématiques de la nutrition en ophtalmologie – application à la dégénérescence maculaire liée à l’âge

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Nutrition in ophthalmology – clinical application to age-related macular degeneration «Let food be your medicine.» This contribution from Hippocrates is still timely addressed, especially in the field of ophthalmology. Observational epidemiology reports close associations between food habits and the risk or prevention of several ocular pathologies such as cataract or Age-related Macular Degeneration (AMD). Anti-oxidant vitamins, minerals and lipids are the nutrients that have been the most widely studied. Interventional epidemiology and experimental works partially corroborated these findings. Unexpectedly, the benefit of long chain omega 3 polyunsaturated fatty acids in the prevention of late AMD was not firmly established in Age-Related Eye Disease Study 2 (AREDS2). Nevertheless, one should not omit to refer to well established data in this field. Still, further works are needed and warranted, especially for better delineating the role of, not only nutrients but also dietary habits, and gene-nutrients interactions.