Heterocyclic rearrangements. Synthesis of 1,2,4-oxadiazolo[2,3-a]pyrimidinium systems and their ring opening into pyrimidineN-oxides

6533b82ffe1ef96bd1294ea2

RESEARCH PRODUCT

Heterocyclic rearrangements. Synthesis of 1,2,4-oxadiazolo[2,3-a]pyrimidinium systems and their ring opening into pyrimidineN-oxides

Vincenzo Frenna Silvestre Buscemi Nicolò Vivona Gabriella Macaluso

subject

chemistry.chemical_classification chemistry.chemical_compound chemistry Pyrimidine Stereochemistry Acetylacetone Organic Chemistry Perchloric acid Ring (chemistry)Medicinal chemistry Bond cleavage Nitrone

description

Reaction des methyl- et phenyl-5 amino-3 oxadiazoles-1,2,4 avec l'acetylacetone ou la benzoylacetone en presence d'acide perchlorique: obtention de methyl- et phenyl-2 methyl- et phenyl-5 methyl-7 oxadiazolo [2,3-a] pyrimidiniums-4 qui se decyclisent ensuite en oxydes-1 d'acylamino-2- et amino-2 methyl-4 methyl- et phenyl-6 pyrimidines

year	journal	country	edition	language
1986-07-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570230442

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