6533b82ffe1ef96bd1294f02
RESEARCH PRODUCT
false
subject
0301 basic medicineNitrileStereochemistryImineGeneral ChemistryCrystal structureCondensed Matter PhysicsRing (chemistry)Medicinal chemistryChlorideD-1Crystal03 medical and health scienceschemistry.chemical_compound030104 developmental biologychemistryPyridinemedicineGeneral Materials Sciencemedicine.drugdescription
The side product of the cyclocondensation reaction between ethyl benzimidazole-2-carboxylate and the nitrile imine of the corresponding hydrazonyl chloride, C20H11BrClN5O, crystallized in two crystal forms. Form (1) is a co-crystal of the target compound (without any chlorine substituent) and a side product containing a Cl atom in position 2 of the bromophenyl group, C20H12BrN5O·0.143C20H11BrClN5O. (2) contains the pure side product. The slightly different conformation of the ring systems leads to a different packing of (1) and (2), but both crystal structures are dominated by π–π interactions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-08-15 | Acta Crystallographica Section E Crystallographic Communications |