Preparation and cytotoxic properties of goethite-based nanoparticles covered with decyldimethyl(dimethylaminoethoxy) silane methiodide

6533b82ffe1ef96bd1294f0a

RESEARCH PRODUCT

Preparation and cytotoxic properties of goethite-based nanoparticles covered with decyldimethyl(dimethylaminoethoxy) silane methiodide

Irina Shestakova Anita Gulbe Radostina Georgieva Anatoly Mishnev Dmitry Zablotsky Edmunds Lukevics Mikhail Maiorov Elmars Blums Alla Zablotskaya Izolda Segal

subject

Goethite Inorganic chemistry Nanoparticle General Chemistry Silane Inorganic Chemistry chemistry.chemical_compound Oleic acid Colloid chemistry Dynamic light scattering visual_art visual_art.visual_art_medium Methiodide Iron oxide nanoparticles Nuclear chemistry

description

The present work describes the synthesis, physico-chemical and biological properties of the first water-soluble goethite nanoparticles covered with biologically active components: oleic acid and cytotoxic decyldimethyl(dimethylaminoethoxy)silane methiodide. The structure of initial goethite nanoparticles synthesized was proved by XRD analysis and the rough estimation of nanoparticles core size gave the value of 8 nm. The size of colloidal water-soluble nanoparticles, determined by dynamic light scattering, was within 19–35 nm. Magnetic properties and cytotoxicity (against HT-1080 and MG-22A tumor cell lines) of the nanoparticles obtained were investigated. Copyright © 2009 John Wiley & Sons, Ltd.

year	journal	country	edition	language
2010-03-01	Applied Organometallic Chemistry

https://doi.org/10.1002/aoc.1573

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