6533b82ffe1ef96bd1295145

RESEARCH PRODUCT

Method for Specific Identification of the Emerging Zoonotic Pathogen Vibrio vulnificus Lineage 3 (Formerly Biotype 3).

Carmen AmaroNaiel BisharatHéctor Carmona-salido

subject

Microbiology (medical)Genetics0303 health sciencesLineage (genetic)030306 microbiologyVirulenceOutbreakBacteriologyVibrio vulnificusBiologybiology.organism_classificationDisease Outbreaks03 medical and health sciencesFish DiseasesSepsisVibrio InfectionsGene duplicationAnimalsHumansComparative genomic analysisZoonotic pathogenVibrio vulnificus030304 developmental biologySpecific identificationVibrio

description

ABSTRACT Vibrio vulnificus is a zoonotic pathogen that is spreading worldwide due to global warming. Lineage 3 (L3; formerly biotype 3) includes the strains of the species with the unique ability to cause fish farm-linked outbreaks of septicemia. The L3 strains emerged recently and are particularly virulent and difficult to identify. Here, we describe a newly developed PCR method based on a comparative genomic study useful for both rapid identification and epidemiological studies of this interesting emerging group. The comparative genomic analysis also revealed the presence of a genetic duplication in the L3 strains that could be related to the unique ability of this lineage to produce septicemia outbreaks.

10.1128/jcm.01763-20https://pubmed.ncbi.nlm.nih.gov/33148703