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RESEARCH PRODUCT
Sustainable production of bioactive compounds from sponges: primmorphs as bioreactors
W. E. G. MüllerMarialuisa MennaS. De RosaFranz BrümmerAnna AielloR. BatelHeinz-christoph SchröderErnesto Fattorussosubject
Phylum PoriferabiologyPulp and paper industrybiology.organism_classificationBioactive compoundMicrobiologyDNA metabolismSpongechemistry.chemical_compoundSequence homologychemistryBioreactorMaricultureSustainable productiondescription
Sponges [phylum Porifera] are a rich source for the isolation of biologically active and pharmacologically valuable compounds with a high potential to become effective drugs for therapeutic use. However, until now, only one compound has been introduced into clinics because of the limited amounts of starting material available for extraction. To overcome this serious problem in line with the rules for a sustainable use of marine resources, the following routes can be pursued; first, chemical synthesis, second, cultivation of sponges in the sea (mariculture), third, growth of sponge specimens in a bioreactor, and fourth, cultivation of sponge cells in vitro in a bioreactor.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2003-01-01 |