6533b82ffe1ef96bd1295b18
RESEARCH PRODUCT
Radical Addition of Dihydroquinoxalin-2-ones to Trifluoromethyl Ketones under Visible-Light Photoredox Catalysis
Jaume Rostoll-berenguerMaría Martín-lópezGonzalo BlayJosé R. PedroCarlos Vilasubject
Organic ChemistryQuímica orgànicaReaccions químiquesdescription
A visible-light photocatalytic radical addition reaction of dihydroquinoxalin-2-ones to trifluoromethyl ketones has been established using Ru(bpy)3Cl2 as photocatalyst, acetonitrile as solvent, and HP Single Blue LED as the source of light. The reaction provides a straightforward approach to the synthesis of dihydroquinoxalin-2-ones bearing a trifluoromethyl-substituted tertiary alcohol moiety in moderate to good yields under mild conditions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-07-06 |