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RESEARCH PRODUCT

A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials

Estela ClimentAna M. CosteroAna M. CosteroKnut RurackMustafa BiyikalMartin UrbanKornelia GawlitzaTomáš DropaRamón Martínez-máñez

subject

Boron CompoundsSarinSilicon dioxideSomanAnalytical chemistrynerve gases010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundSomanQUIMICA ANALITICAmedicineChemical Warfare AgentsTabunNerve agenthybrid sensor materialsChromatography010405 organic chemistryOrganic ChemistryQUIMICA INORGANICAGeneral ChemistrySilicon DioxideFluorescenceSarinOrganophosphates0104 chemical scienceschemistrychemical warfare agentstest strip analysisProthrombin TimefluorescenceBODIPYMesoporous materialNerve Agentsmedicine.drug

description

Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the mu g m(-3) range in a few seconds.

10.13039/501100003359https://dx.doi.org/10.1002/chem.201601269