6533b830fe1ef96bd1296602
RESEARCH PRODUCT
Crystal structure of the tripeptideN-(benzyloxycarbonyl)glycylglycyl-L-norvaline
Sumesh Nicholassubject
conformationchemistry.chemical_classificationcrystal structureStereochemistryHydrogen bondGeneral ChemistryTripeptideCrystal structurehydrogen bondingCondensed Matter PhysicsData ReportspeptidenorvalineAmino acidlcsh:Chemistrychemistry.chemical_compoundResidue (chemistry)lcsh:QD1-999chemistryValineSide chainGeneral Materials ScienceNorvalineglycinedescription
The title tripeptide, C17H23N3O6, contains a nonproteinogenic C-terminal amino acid residue, norvaline, which is an isomer of the amino acid valine. Norvaline, unlike valine, has an unbranched side chain. The molecule has a Gly–Gly segment which adopts an extended conformation. The norvaline residue also adopts an extended backbone conformation while its side chain has ag+tconformation. In the crystal lattice, N—H...O and O—H...O hydrogen bonds stabilize the packing. Molecules translated along the crystallographicaaxis associate through an N—H...O hydrogen bond. The remaining three hydrogen bonds are between molecules related by a21screw axis.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-02-28 | Acta Crystallographica Section E Crystallographic Communications |