6533b830fe1ef96bd12967b0
RESEARCH PRODUCT
The neural feedback loop between the brain and adipose tissues
Luc Pénicaudsubject
MESH: Feedback Physiological[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionPhysiologicalAdipokineAdipose tissueWhite adipose tissueBiologyAutonomic Nervous SystemMESH : Adipose TissueEnergy homeostasisMESH : Autonomic Nervous SystemFeedbackMESH: Autonomic Nervous System[ SDV.NEU.SC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesMESH: BrainBrown adipose tissuemedicineLipolysisAnimalsHumansMESH: AnimalsComputingMilieux_MISCELLANEOUSFeedback PhysiologicalMESH: HumansLeptinMESH : HumansMESH: Energy MetabolismBrain[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesMESH : Feedback PhysiologicalNeurosecretory SystemsCell biologyMESH : Energy MetabolismAutonomic nervous systemmedicine.anatomical_structureMESH : BrainAdipose TissueMESH: Neurosecretory SystemsMESH : AnimalsEnergy Metabolism[SDV.AEN]Life Sciences [q-bio]/Food and NutritionMESH : Neurosecretory Systems[SDV.NEU.SC] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesMESH: Adipose Tissuedescription
Communication également publiée dans le livre "Adipose tissue development: from animal models to clinical conditions" (ISBN 978-3-8055-9450-9) de C. Levy-Marchal et L. Pénicaud (eds); There are more and more data supporting the importance of nervous regulation of both white and brown adipose tissue mass. This short paper will review the different physiological parameters which are regulated such as metabolism (lipolysis and thermogeneis), secretory activity (leptin and other adipokines) but also to plasticity of adipose tissues (proliferation differentiation and apoptosis). The sensory innervation of white adipose issue and its putative role will be also described. Altogether these results showed the presence of a neural feedback loop between adipose tissues and the brain which plays a major role in the regulation of energy homeostasis and has been shown to be altered in physiologic as well as in metabolic pathologies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-03-12 |