6533b830fe1ef96bd1296f2f

RESEARCH PRODUCT

ChemInform Abstract: Iodocyclization of o-Alkynylbenzamides Revisited: Formation of Isobenzofuran-1(3H)-imines and 1H-Isochromen-1-imines Instead of Lactams.

Dieter SchollmeyerTill OpatzLars AndernachBernd F. StraubClaudine Schlemmer

subject

chemistry.chemical_compoundIsobenzofuranchemistryHalogenationGeneral MedicineMedicinal chemistryBenzopyran

description

Remarkably, isobenzofuran and benzopyran derivatives are obtained by the title reaction and not as described in earlier publications five- or six-membered lactams.

https://doi.org/10.1002/chin.201316071