Clinical recrudescence of chronic untreated P. malariae infection after BNT162b2 CoVID-19 vaccine

6533b830fe1ef96bd1297106

RESEARCH PRODUCT

Clinical recrudescence of chronic untreated P. malariae infection after BNT162b2 CoVID-19 vaccine

G Ciusa F Guida Marascia R Virruso A Angheben G Guaraldi A Cascio

subject

Plasmodium malariae Infectious Diseases Plasmodium malariae.BNT162b2 Chronic malaria BNT162b2; Chronic malaria; CoVID-19 vaccine; Malaria; Plasmodium malariae CoVID-19 vaccine Malaria

description

We described a case of clinical reactivation of chronic P. malariae infection following CoVID-19 vaccination with BNT162b2 (Pifzer-Biontech CoVID-19 vaccine) in a 48-year old Italian man.The patient came to our attention for fever of unknown origin show a quartan pattern (every third day) associated to splenomegaly, the onset of the fever occurred one month after CoVID-19 vaccination with BNT162b2. P. malariae was diagnosed using CarestartTM malaria rapid test and Polymerase-Chain Reaction. Post-vaccine transient reduction of immune reactivity is described in literature, although the mechanism is unknown.(c) 2022 Published by Elsevier Ltd.CC_BY_NC_ND_4.0

year	journal	country	edition	language
2022-01-01	IDCases

https://doi.org/10.1016/j.idcr.2022.e01456

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