6533b830fe1ef96bd1297a18

RESEARCH PRODUCT

New Glass Capillary Gas-Chromatographic Methods for Metabolites in Urine and Serum

Werner Dosch

subject

chemistry.chemical_compoundChromatographyChemistryCapillary actionExtraction (chemistry)Column switchingUrineDerivatizationDimethyl ester

description

The analytical system suggested in this paper is a further development of pre-chromatographic methods and of column switching techniques described in previous papers1,2,3.In order to use modern gas-chromatographic techniques for the determination of metabolites in urine and serum quick and reliable pre-chromatographic methods for extraction, concentration and derivatization must be developed which give final (dosage) volumes of 5 to 10 μl with starting sample volumes of 0.1 ml of urine or 5 ml of serum as described by Dunges4.

https://doi.org/10.1007/978-1-4684-8977-4_157