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RESEARCH PRODUCT
Pneumococcal vaccination in celiac disease
Fabio IngravalleGiorgio AbbateGabrio BassottiAntonio CarroccioFulvio BonettiPasquale MansuetoGiovanni CasellaVincenzo VillanacciClaudio Montisubject
Settore MED/09 - Medicina InternaDiseaseOpportunistic InfectionsHypersplenismPneumococcal InfectionsPneumococcal VaccinesImmunocompromised Host03 medical and health sciences0302 clinical medicineRisk FactorshyposplenismAnimalsHumansCeliac diseasepneumoniaMedicineinfectionschemistry.chemical_classificationHepatologybusiness.industryVaccinationGastroenterologynutritional and metabolic diseasesCeliac disease; hyposplenism; infections; pneumococcal vaccination; pneumoniaProtective FactorsPrognosisGluteninfectiondigestive system diseaseschemistryInfectious disease (medical specialty)030220 oncology & carcinogenesisPneumococcal vaccinationImmunology030211 gastroenterology & hepatologypneumococcal vaccinationbusinessSpleendescription
Introduction: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen function should be useful to select patients who may benefit from vaccination to reduce the risk of pneumococcal disease. Different strategies could be employed: physicians could search for signs of hyposplenism on peripheral blood smear or abdominal ultrasound. However, the best strategy to identify which patients will benefit from pneumococcal vaccination has not yet been defined.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2019-01-01 | Expert Review of Gastroenterology & Hepatology |