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RESEARCH PRODUCT

A new polyketide from the bark of Hypericum roeperianum Schimp. (Hypericaceae)

François DamenOlive Monique F. DemgneGabin Thierry M. BitchagnoIlhami CelikJames D. Simo MpetgaSimplice Beaudelaire TankeoTill OpatzVictor KuetePierre Tane

subject

description

The isolation and spectroscopic data of a hitherto undescribed polyketide (1) from Hypericum roeperianum Schimp. (Hypericaceae) together with six known compounds (2–7) is herein reported. The structure elucidation is based on extensive 1D- and 2D-NMR, infrared, UV and MS experiments. The structures of the known compounds were confirmed by comparison of their spectroscopic data with those of similar reported compounds in the literature. Some of the isolated compounds had a significant activity against a panel of multidrug-resistant bacterial strains.

https://dx.doi.org/10.6084/m9.figshare.9980882.v1